Treatment Of Fibromyalgia

Until the advent of alternative medicine methods (from the anti-aging medicine branch) the standard multidisciplinary treatment protocol described below had a success rate of about 40 to 50%. When a thorough assessment of the hormone status is done and the missing items are replaced, as described under "alternative medicine treatment of fibromyalgia" below, the treatment success rate can be as high as 85 to 90%. It is important to be aware that there are various degrees of severity of fibromyalgia, which correlate to various degrees of hormone and nutritional deficiencies (at the level of brain hormones and of the hormone glands of the body). Whatever is missing has to be supplemented in natural form (bioidentical hormones and nutraceuticals). I will deal with both treatment approaches under separate headings, but they can be combined.

Standard Treatment of Fibromyalgia:

Treatment of fibromyalgia consists of a comprehensive program, where the various factors that are observed in the patient are addressed. The sleeping disturbance, if present, is treated with cyclobenzaprine (brand name: Flexeril, Flexitec) at bedtime. This medication, which is an tricyclic antidepressant, is used mainly as a muscle relaxant, but has been found in fibromyalgia patients to restore abnormal sleep patterns.

Another medication that can be used for this is the antidepressant trazodone ( brand name: Desyrel, Trazorel), which when taken at bedtime seems to help not only to normalize the sleeping pattern, but also lift the mood (antidepressant effect) and thus help with some of the myalgias (painful muscles).

Multidisciplinary treatment approach for fibromyalgia
Target symptom:Treatment modality:
muscle deconditioningswimming, aquatherapy, walking, and mild stretching exercises (better tolerated with IceWave patches from Lifewave in place)
muscle spasm and tender spots

1) Local heat treatments, massage therapy, chiropractic adjustments and physiotherapy, aquatherapy

2) trigger point injections by the physician
sleep disordercyclobenzaprine (brand name: Flexeril, Flexitec) or trazodone (brand name: Desyrel, Trazorel), however see remarks on the use of conventional drugs under "Alternative Medicine Treatment" below
mild to moderate depression SSRI antidepressant medication (but see remarks on the use of conventional drugs under "Alternative Medicine Treatment" below)
anxietyyoga, meditation, self-hypnosis, prayer, cognitive and behavior therapy, psychological counseling; bioidentical hormone replacement will often also treat anxiety naturally (see Ref.8)

Many of the SSRI antidepressants have a similar effect as trazodone. They also help to lift depression, which is another symptom complex that the physician will treat. Physical activities in the form of swimming, aquatherapy, walking, and mild stretching exercises are instituted. Often it might be best to do this as part of a local fibromyalgia support group, as motivation could otherwise be a problem. Local heat treatments, massage therapy, minor chiropractic adjustments for spinal malalignments are all useful modalities as is physiotherapy for flare-ups of the muscle aches and pains. Trigger point injections by the physician with 1% Xylocaine (occasionally with a small amount of cortisone mixed in) may be very useful for more painful muscles.

Meditation, self-hypnosis,yoga, cognitive and behavior modification therapy are all useful adjunctive methods to help with the associated anxiety and depression along the medications mentioned above. These latter methods help with coping strategies in the treatment of fibromyalgia (Ref. 4).

Alternative Medicine Treatment of Fibromyalgia:

According to the interviews with a number of anti-aging doctors contained in Suzanne Somers' book "Breakthrough" (Ref.8) fibromyalgia is often associated with hypothyroidism and may include other hormone weaknesses (weak adrenal glands, low human growth hormone levels) and also often low steroid hormones (testosterone, estradiol, progesterone). This can be determined with appropriate blood tests (T3, T4, 24 hour urine for cortisol, DHEA, IGF-1), which your regular physician may not be comfortable ordering. However, any of the anti-aging physicians listed in the back of Ref.8 would have no problems ordering and treating this.
Here are the major treatment steps using an anti-aging type approach for the treatment of fibromyalgia:


1. This new approach to treat fibromyalgia puts emphasis on detoxifying the body, starting a low glycemic well balanced diet, exercising regularly and keeping you away from as many conventional drugs as possible including antidepressants (including trazodone mentioned above). The reason for this is that all of the hormones including the brain hormone serotonin need to be balanced to treat fibromyalgia successfully.


2. Insomnia is treated with a combination of melatonin capsules in the dosage range of 3 mg to 15 mg at bedtime. Dr. Lichten (Ref. 9) treats insomnia with a combination of L-Tryptophan 500 mg to 1000 mg combined with 125-250 mg of sublingual GABA at bedtime. This can also be combined with melatonin as indicated. Dr. Lichten treats with GABA only for 5 to 6 nights per week as tolerance can quickly develop through saturation of GABA receptors in the brain. But by taking a GABA rest for 1 to 2 days in a week the receptors reset themselves.


3. Another important point to note is that magnesium deficiency leads to increased anxiety and restless leg syndrome. Chronic insomnia also depletes the cells' magnesium content (Ref.9). Dr. Lichten recommends taking 1000 mg of magnesium supplements daily. Alternatively a couple of teaspoons of milk of magnesia will also provide the body with the equivalent of magnesium and keep the bowels regulated at the same time.


4. Vitamin D sublingual drops at a dose of 1000 mg to 5000 mg have a very beneficial effect on getting a good night's sleep. However, we do know from the more recent literature that higher doses of vitamin D help prevent diabetes, cancer, and treat chronic muscle aches and pains, particularly of the fibromyalgia type (Ref. 9). Dr. Lichten recommends that your doctor should order a 25-hydroxyvitamin D level initially and bring this up to and above 50-6- ng/mL with vitamin D drop supplementation.


5. Fibromyalgia patients are not all the same when saliva hormone tests and blood screening tests are analyzed. However, the physician will find that invariably there are some deficiencies in some of the anabolic type hormones (testosterone, human growth hormone and DHEA). Whatever hormone is weak, needs to be replaced by bio-identical hormone replacement (Ref. 10 and 11). Postmenopausal women need extra hormonal replacements as described under menopause, males need replacements as described under male menopause. If IGF-1 tests below 80 ng/mL, this indicates a growth hormone deficiency. In such cases somatotropin (brand name: Saizen) is given with a low dose of 1 international unit per day subcutaneously for 5 to 7 days per week (Ref. 9). Dr. Lichten describes several cases of astounding recoveries from fibromyalgia using low dose human growth hormone injections in this reference.


6. Nutraceuticals (high dose vitamins and minerals as described under vitamins, minerals and supplements) are also required to stimulate the mitochondria to supply the body's cells with adequate energy. As often the digestive tract is slow pancreatic enzymes as supplements can improve the absorption of food, vitamins and supplements (Ref. 9).


7. Exercise is now possible when the muscle aches are under control and this should consist of a regular walking program, swimming, ballroom dancing etc. This is important as endorphins that are released in the brain by exercise will help to control the muscle aches and pains as well. Yoga exercises, meditation, prayer and self-hypnosis treatments will help to overcome anger and resentments that would otherwise feed into the adrenalin release/muscle tension cycle. Patience is required to await the full benefit of all of these treatment factors. It often takes 6 to 12 months for a good response to all of these factors (Ref. 9, 10, 11).


8. Detoxification of the body from lead, mercury and other heavy metals by intravenous treatments (Glutathione 750 mg to 1250 mg, mixed with 10,000 mg of vitamin C in Ringer's lactate) and given in intervals twice per week up to 20 to 30 treatments in total will help the patient to regain a lot of the lost energy. This intravenous treatment can also been augmented by adding a number of minerals (called "Myer's cocktail"), which help to balance the cell metabolism. This latter treatment possibility is particularly important in those cases where fibromyalgia presents together with irritable bowel syndrome. In these cases there can be malabsorption of minerals and nutrients and Myer's cocktail can lead to remarkable improvements.

All of these points should be done in combination and should be co-ordinated with the items mentioned in the "multidisciplinary treatment approach for fibromyalgia" table above to get the best possible treatment success.


Another link re. fibromyalgia treatment.

Home page Arthritis Fibromyalgia

 

 

 

Disclaimer:

This outline is only a teaching aid to patients and should stimulate you to ask the right questions when seeing your doctor. However, the responsibility of treatment stays in the hands of your doctor and you.

References:

1. G.Littlejohn  Aust Fam Physician 2001 Apr;30(4):327-333.

2. LS Brecher et al. J Am Osteopath Assoc 2001 Apr;101(4 Suppl Pt 2):S12-17.

3. The Merck Manual, 7th edition, by M. H. Beers et al., Whitehouse Station, N.J., 1999. Chapter 59.

4. ABC of rheumatology, second edition, edited by Michael L. Snaith , M.D., BMJ Books, 1999. Chapter 6. Fibromyalgia Syndrome.

5. B Mukerji et al. Angiology 1995 May;46(5):425-430.

6. Ferri: Ferri's Clinical Advisor: Instant Diagnosis and Treatment, 2004 ed., Copyright © 2004 Mosby, Inc.

7. Rakel: Conn's Current Therapy 2004, 56th ed., Copyright © 2004 Elsevier

8. Suzanne Somers: "Breakthrough" Eight Steps to Wellness-- Life-altering Secrets from Today's Cutting-edge Doctors", Crown Publishers, 2008

9. Dr. Edward M. Lichten: Textbook of bio-identical hormones. ©2007 Foundation for Anti-Aging Research, Birmingham, Michigan, USA

10. Dr. Michael E. Platt: The Miracle of Bio-Identical Hormones; 2nd edition, © 2007 Clancy Lane Publishing, Rancho Mirage, Ca/USA

11. Dr. Daniel G. Amen: Magnificent Mind at any Age; © 2008 Three Rivers Press, New York, USA

Last Modified: May 28, 2010